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There were fewevents in people with early signs of the disease.
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While dermalpenetration of solvents typically is negligible at low air con-centrations, the ACGIH and OSHA note that this route forsome substances may be significant at high air concentra-tions, hence an occupational “skin” designation, applicablein confined spaces or areas where respiratory protection(e.g., use of air-purifying or air-supplied respirators) limitspotential for inhalation. The International Classi?cation ofFunctioning, Disability, and Health (ICF), endorsed by WHO in 2001, provides additional in-formation related to functioning and disability associated with health conditions.